Integrated regional and global coordination and financing
mechanism of R&D for diseases that disproportionately affect developing
countries - the ANDI model
1) ANDI - African Network for Drugs and Diagnostics Innovation,
United Nations Economic Commission for Africa, Addis Ababa, Ethiopia;
2) TDR - UNICEF/UNDP/World Bank/WHO Special Programme for Research and
Training in Tropical Diseases, World Health Organization, Geneva, Switzerland.
Description of the proposal:
A coordinating and financing model for R&D is proposed that is based on the formal
establishment of regional and sub-regional networks under representative
governance. These can address finance and sustain R&D innovation for diseases
that disproportionately affect developing countries. By linking these networks into a
global 'Network of Networks' model, supported by a small central secretariat, a
coherent approach to address the objectives of the GSPOA can be developed.
This approach, with funds, staff and autonomy based within the regions, provides a
decentralized approach to decision making that addresses local needs. It also offers
multiple options for financing, as the networks can access global, regional, sub-
regional and nationally available resources. Many of these opportunities would not
be available for an international initiative. The networks can also negotiate in kind
resources e.g. through national research councils, in a way that would not be
possible for a centralized global organization.
This approach is complimentary to, and not in competition with, existing disease-
focused approaches such as public private or product development partnerships
(PPPs or PDPs). It also allows for the development of local public private
The proposed mechanism has a very strong capacity building element, through
enhanced intra-regional collaboration, building on regional centres of excellence.